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DKK4 Antibody

DKK4 Antibody

Item no.	OACA07345
Manufacturer	AVIVA Systems Biology
Amount	50 ul
Category	Oncology Neuroscience Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Neural Mitochondrial Function Antibodies By Cell Type Obesity Immunohistochemistry Western Blot ELISA Lipoprotein Receptors & Associated Proteins Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]"Function and biological roles of the Dickkopf family of Wnt modulators."Niehrs C.Oncogene 25:7469-7481(2005). [2]"Signal peptide prediction based on analysis of experimentally verified cleavage sites."Zhang Z., Henzel W.J.Protein Sci. 13:2819-2824(2003). [3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."The MGC Project TeamGenome Res. 14:2121-2127(2003).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	dickkopf-4;dickkopf-related protein 4;DKK-4;hDkk-4.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	DKK4
Gene Fullname	dickkopf WNT signaling pathway inhibitor 4
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Nucleotide accession_num	NM_014420
Protein accession_num	NP_055235
Protein name	Dickkopf-related protein 4
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Dickkopf-related protein 4 protein (19-224AA)
Formulation	PBS with, 50% glycerol, pH7.3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 10/30/2025

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