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MAGEC2 Antibody

MAGEC2 Antibody

Item no.	OACA07556
Manufacturer	AVIVA Systems Biology
Amount	50 ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Immunohistochemistry ELISA Primary Antibodies Astrocytoma By Organ Breast Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]"MAGE-B5, MAGE-B6, MAGE-C2, and MAGE-C3: four new members of the MAGE family with tumor-specific expression."Lucas S., De Plaen E., Boon T.Int. J. Cancer 87:55-60(2000). [2]"Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies."Wang Y., Han K.-J., Pang X.-W., Vaughan H.A., Qu W., Dong X.-Y., Peng J.-R., Zhao H.-T., Rui J.-A., Leng X.-S., Cebon J., Burgess A.W., Chen W.-F.J. Immunol. 169:1102-1109(2002). [3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."The MGC Project TeamGenome Res. 14:2121-2127(2004).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	cancer/testis antigen 10;CT10;HCA587;hepatocellular cancer antigen 587;hepatocellular carcinoma-associated antigen 587;MAGE-C2 antigen;MAGEE1;MAGE-E1 antigen;melanoma antigen family C,2;melanoma antigen family C2;melanoma antigen,family E,1,cancer/testis specific;melanoma-associated antigen C2.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	MAGEC2
Gene Fullname	MAGE family member C2
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.
Nucleotide accession_num	NM_016249
Protein accession_num	NP_057333
Protein name	Melanoma-associated antigen C2
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Melanoma-associated antigen C2 protein (1-150AA)
Formulation	PBS with, 50% glycerol, pH7.3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 12/25/2025

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