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RNF139 Antibody

RNF139 Antibody

Item no.	OACA08886
Manufacturer	AVIVA Systems Biology
Amount	50 ul
Category	Metabolism Diabetes Cholesterol & Lipid Metabolism Antibodies Obesity Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining Other Lipid\Cholesterol Metabolism Modulators
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E3 ubiquitin-protein ligase RNF139;HRCA1;multiple membrane spanning receptor TRC8;patched related protein translocated in renal cancer;RCA1;RING finger protein 139;RING-type E3 ubiquitin transferase RNF139;translocation in renal carcinoma on chromosome 8 protein;translocation in renal carcinoma,chromosome 8;TRC8.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	RNF139
Gene Fullname	ring finger protein 139
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	E3-ubiquitin ligase; acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination. May be required for EIF3 complex ubiquitination. May function as a signaling receptor.
Nucleotide accession_num	NM_007218
Protein accession_num	NP_009149
Protein name	E3 ubiquitin-protein ligase RNF139
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human E3 ubiquitin-protein ligase RNF139 protein (510-664AA)
Formulation	PBS with, 50% glycerol, pH7.3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 12/25/2025

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