Comparison

DOCK7 Antibody

Item no. OACA09922
Manufacturer AVIVA Systems Biology
Amount 50 ug
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IF, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
Purity >95%
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias dedicator of cytokinesis protein 7;DEE23;EIEE23;ZIR2.
Shipping Condition Cool pack
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Gene symbol
DOCK7
Gene Fullname
dedicator of cytokinesis 7
Product format
Liquid
Reconstitution and storage
-20°C or -80°C
Description of target
Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).
Nucleotide accession_num
NM_001271999
Protein accession_num
NP_001258928
Protein name
Dedicator of cytokinesis protein 7
Clonality
Polyclonal
Purification
Protein G Purified
Immunogen
Recombinant Human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
Formulation
50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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