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TRIB3 Antibody

TRIB3 Antibody

Item no.	OACA09929
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies CHiP Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C20orf97;neuronal cell death inducible putative kinase;Neuronal cell death-inducible putative kinase;NIPK;p65-interacting inhibitor of NF-kappaB;p65-interacting inhibitor of NF-kappa-B;SINK;SKIP3;TRB3;TRB-3;tribbles homolog 3.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	TRIB3
Gene Fullname	tribbles pseudokinase 3
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA.
Nucleotide accession_num	NM_001301188
Protein accession_num	NP_001288117
Protein name	Tribbles homolog 3
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Tribbles homolog 3 protein (152-325AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 10/30/2025

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