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SMO Antibody

SMO Antibody

Item no.	OACA09939
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Neuroscience Neural Signaling Neural Development Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Sarcoma Cell Biology Cytoskeleton Immunohistochemistry Western Blot ELISA Immunofluorescence Motor proteins Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CRJS;frizzled family member 11;FZD11;Gx;PHLS;protein Gx;seven transmembrane helix receptor;SMOH;smoothened homolog;smoothened,frizzled family receptor;smoothened,seven transmembrane spanning receptor.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	SMO
Gene Fullname	smoothened, frizzled class receptor
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7, GLI2 and GLI3 in the cilia (PubMed:19592253). Interacts with DLG5 at the ciliary base to induce the accumulation of KIF7 and GLI2 at the ciliary tip for GLI2 activation (By similarity).
Nucleotide accession_num	NM_005631
Protein accession_num	NP_005622
Protein name	Smoothened homolog
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Smoothened homolog protein (28-233AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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