« Back
Home /
PINK1 Antibody

PINK1 Antibody

Item no.	OACA09942
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Neuroscience Neuroinflammation Metabolism Diabetes Neural Mitochondrial Function Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Obesity Cell Status Immunohistochemistry Western Blot ELISA Autophagy Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BRPK;PARK6;protein kinase BRPK;PTEN induced putative kinase 1;PTEN-induced putative kinase protein 1;serine/threonine-protein kinase PINK1,mitochondrial.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	PINK1
Gene Fullname	PTEN induced kinase 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PRKN (PubMed:14607334, PubMed:15087508, PubMed:19229105, PubMed:19966284, PubMed:20404107, PubMed:20798600, PubMed:23620051, PubMed:23754282, PubMed:23933751, PubMed:24660806, PubMed:24751536, PubMed:24784582, PubMed:24896179, PubMed:25527291). Targets PRKN to dysfunctional depolarized mitochondria through the phosphorylation of MFN2 (PubMed:23620051). Activates PRKN in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PRKN and (2) mediating phosphorylation of ubiquitin, converting PRKN to its fully-active form (PubMed:24660806, PubMed:24751536, PubMed:24784582, PubMed:25527291). Required for ubiquinone reduction by mitochondrial complex I by mediating phosphorylation of complex I subunit NDUFA10 (By similarity).
Nucleotide accession_num	NM_032409
Protein accession_num	NP_115785
Protein name	Serine/threonine-protein kinase PINK1, mitochondrial
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Serine/threonine-protein kinase PINK1, mitochondrial protein (162-272AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

OACA09942-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 50 ug

available

Delivery expected until 10/30/2025

Express Delivery: Save 2 days

Compare

Add to wishlist

Get an offer