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SMURF1 Antibody

SMURF1 Antibody

Item no.	OACA09952
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Neuroscience Neuroinflammation Neural Mitochondrial Function Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Cytoskeleton Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunofluorescence Autophagy Primary Antibodies Immunostaining small GTPases Rho Subfamily
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E3 ubiquitin ligase SMURF1;E3 ubiquitin-protein ligase SMURF1;HECT-type E3 ubiquitin transferase SMURF1;hSMURF1;Smad ubiquitination regulatory factor 1;Smad-specific E3 ubiquitin ligase 1;SMAD-specific E3 ubiquitin-protein ligase 1.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	SMURF1
Gene Fullname	SMAD specific E3 ubiquitin protein ligase 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Promotes ubiquitination and subsequent proteasomal degradation of MAVS (PubMed:23087404). Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Nucleotide accession_num	NM_001199847
Protein accession_num	NP_001186776
Protein name	E3 ubiquitin-protein ligase SMURF1
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human E3 ubiquitin-protein ligase SMURF1 protein (198-374AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 10/30/2025

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