Comparison

SNX17 Antibody

Item no. OACA10066
Manufacturer AVIVA Systems Biology
Amount 50 ug
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IF, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
Purity >95%
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias sorting nexin-17.
Shipping Condition Cool pack
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Gene symbol
SNX17
Gene Fullname
sorting nexin 17
Product format
Liquid
Reconstitution and storage
-20°C or -80°C
Description of target
Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).
Nucleotide accession_num
NM_001267060
Protein accession_num
NP_001253989
Protein name
Sorting nexin-17
Clonality
Polyclonal
Purification
Protein G Purified
Immunogen
Recombinant Human Sorting nexin-17 protein (280-457AA)
Formulation
50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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