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TRIM25 Antibody

TRIM25 Antibody

Item no.	OACA10067
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E3 ubiquitin/ISG15 ligase TRIM25;EFP;estrogen-responsive finger protein;RING finger protein 147;RING-type E3 ubiquitin transferase;RING-type E3 ubiquitin transferase TRIM25;RNF147;tripartite motif protein TRIM25;tripartite motif-containing protein 25;ubiquitin/ISG15-conjugating enzyme TRIM25;Z147;Zinc finger protein 147;zinc finger protein 147 (estrogen-responsive finger protein);zinc finger protein-147;ZNF147.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	TRIM25
Gene Fullname	tripartite motif containing 25
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3 (PubMed:22452784).
Nucleotide accession_num	NM_005082
Protein accession_num	NP_005073
Protein name	E3 ubiquitin/ISG15 ligase TRIM25
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human E3 ubiquitin/ISG15 ligase TRIM25 protein (81-272AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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