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DHX36 Antibody

DHX36 Antibody

Item no.	OACA10241
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma ELISA Immunofluorescence Primary Antibodies By Organ Bladder Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ATP-dependent DNA/RNA helicase DHX36;ATP-dependent RNA helicase DHX36;DDX36;DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 36;DEAD/H box polypeptide 36;DEAH (Asp-Glu-Ala-His) box polypeptide 36;DEAH box protein 36;G4 resolvase-1;G4R1;G4-resolvase 1;MLEL1;MLE-like protein 1;probable ATP-dependent RNA helicase DHX36;RHAU;RNA helicase associated with AU-rich element ARE;RNA helicase associated with AU-rich element protein.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	DHX36
Gene Fullname	DEAH-box helicase 36
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Proposed to have a global role in regulating mRNA expression including transcriptional regulation and mRNA stability. Binds with high affinity to and resolves tetramolecular RNA and DNA quadruplex structures. Unwinds intramolecular quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regulates their expression. Binds to telomerase RNA template component (TERC) 5'-end (nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5'-end to promote P1 helix formation; the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification.
Nucleotide accession_num	NM_001114397
Protein accession_num	NP_001107869
Protein name	ATP-dependent RNA helicase DHX36
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human ATP-dependent RNA helicase DHX36 protein (68-181AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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