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NLRX1 Antibody

NLRX1 Antibody

Item no.	OACA10371
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Antibodies By Cell Type Carcinoma Cell Biology Cell Status Immunohistochemistry ELISA Autophagy Primary Antibodies By Organ Bladder Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	caterpiller protein 11.3;CLR11.3;DLNB26;NLR family member X1;NOD26;NOD5;NOD9;NOD-like receptor X1;nucleotide-binding oligomerization domain protein 26;nucleotide-binding oligomerization domain protein 5;nucleotide-binding oligomerization domain protein 9;nucleotide-binding oligomerization domain,leucine rich repeat containing X1.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	NLRX1
Gene Fullname	NLR family member X1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Instead, promotes autophagy by interacting with TUFM and subsequently recruiting the autophagy-related proteins ATG5 and ATG12 (PubMed:22749352). Regulates also MAVS-dependent NLRP3 inflammasome activation to attenuate apoptosis (PubMed:27393910). Has no inhibitory function on NF-kappa-B signaling pathway, but enhances NF-kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).
Nucleotide accession_num	NM_001282143
Protein accession_num	NP_001269072
Protein name	NLR family member X1
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human NLR family member X1 protein (45-205AA)
Formulation	50% Glycerol, 0.01M PBS, pH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 10/30/2025

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