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PHLDA3 Antibody

PHLDA3 Antibody

Item no.	OACA10388
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Immunohistochemistry ELISA Immunofluorescence Primary Antibodies Astrocytoma By Organ Breast Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	pleckstrin homology-like domain family A member 3;pleckstrin homology-like domain,family A,member 2;TDAG51/Ipl homolog 1;TIH1.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	PHLDA3
Gene Fullname	pleckstrin homology like domain family A member 3
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
Nucleotide accession_num	NM_012396
Protein accession_num	NP_036528
Protein name	Pleckstrin homology-like domain family A member 3
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Pleckstrin homology-like domain family A member 3 protein (43-95AA)
Formulation	50% Glycerol, 0.01M PBS, pH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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