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TRADD Antibody

TRADD Antibody

Item no.	OACA10565
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Mesothelioma Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunofluorescence Senescence Primary Antibodies By Organ Lung Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IP, IHC, ELISA
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Hs.89862;TNFR1-associated death domain protein;TNFRSF1A-associated via death domain;tumor necrosis factor receptor type 1 associated death domain protein;tumor necrosis factor receptor type 1-associated DEATH domain protein;tumor necrosis factor receptor-1-associated protein.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	WB: 1:500~5000IHC: 1:20~200IF: 1:50~200IP: 1:200~2000
Gene symbol	TRADD
Gene Fullname	TNFRSF1A associated via death domain
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Nucleotide accession_num	NM_001323552
Protein accession_num	NP_001310481
Protein name	Tumor necrosis factor receptor type 1-associated DEATH domain protein
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Tumor necrosis factor receptor type 1-associated DEATH domain protein (1-312AA)
Formulation	50% Glycerol, 0.01M PBS, pH 7.4
Concentration	Varies by lot. See vial for concentration.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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