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SAMD8 Antibody

SAMD8 Antibody

Item no.	OACA10618
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Metabolism Glucose Homeostasis Antibodies Obesity Immunohistochemistry ELISA Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ceramide phosphoethanolamine synthase;CPE synthase;epididymis luminal protein 177;epididymis secretory sperm binding protein Li 181mP;HEL-177;HEL-S-181mP;SAM domain-containing protein 8;SMSr;sphingomyelin synthase related;sphingomyelin synthase-related protein 1;sterile alpha motif domain-containing protein 8.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	SAMD8
Gene Fullname	sterile alpha motif domain containing 8
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway.
Nucleotide accession_num	NM_001174156
Protein accession_num	NP_001167627
Protein name	Sphingomyelin synthase-related protein 1
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Sphingomyelin synthase-related protein 1 protein (1-152AA)
Formulation	50% Glycerol, 0.01M PBS, pH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 10/30/2025

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