Comparison

TIMP1 Antibody

Item no. OACD00212
Manufacturer AVIVA Systems Biology
Amount 100 ul
Category
Type Antibody Monoclonal
Format Liquid
Applications WB, IP, IHC, ICC
Specific against Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias metalloproteinase inhibitor 1;Timp;TIMP-1;tissue inhibitor of metallopeptidase 1;tissue inhibitor of metalloproteinase 1;tissue inhibitor of metalloproteinases 1.
Shipping Condition Cool pack
Available
Manufacturer - Type
Monoclonal Antibody
Manufacturer - Category
Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Manufacturer - Application Additional Information
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-1:5000
Optimal working dilutions must be determined by end user.
Gene symbol
Timp1
Gene Fullname
TIMP metallopeptidase inhibitor 1
Product format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution and storage
2°C to 8°C|-20°C
Description of target
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells; procathepsin L is required for maximal activity.
Nucleotide accession_num
NM_053819.1
Protein accession_num
NP_446271.1
Protein name
Metalloproteinase inhibitor 1
Clonality
Monoclonal
Purification
Protein A/G Purified
Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Concentration
1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close