ADAM17 Antibody (OACD01395)

Item no.	OACD01395
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Molecular Targets for Neuroscience Infectious Diseases Viral Infections Coronavirus (COVID-19) Antibodies By Cell Type Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Immunohistochemistry Western Blot Immunocytochemistry Cardiovascular Research Heart Failure Myocardial Infarction Primary Antibodies Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ICC
Specific against	other
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Shipping Temperature	Wet Ice
Product format	Liquid
Reconstitution and storage	Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Description of target	Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2.
Protein name	Disintegrin and metalloproteinase domain-containing protein 17
Clonality	Polyclonal
Purification	Antigen-specific affinity chromatography
Immunogen	Range: Lys226 - Arg473
Formulation	PBS, pH7.4, containing 0.02% NaN3, 50% glycerol

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OACD01395-datasheet.pdf

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Amount: 100 ul

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Delivery expected until 10/30/2025

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