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CASP1 Antibody

CASP1 Antibody

Item no.	OACD02184
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Neural Signaling Antibodies Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Cell Status Apoptosis Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ICC
Specific against	Human (Homo sapiens), Pig (Porcine, Sus scrofa domesticus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CASP-1;caspase 1,apoptosis-related cysteine peptidase (interleukin 1,beta,convertase);caspase-1;ICE;IL-1 beta-converting enzyme;IL-1BC;interleukin-1 beta convertase;interleukin-1 beta converting enzyme;Interleukin-1 beta-converting enzyme;p45.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	WB: 0.5-2 ug/mLIHC: 5-20 ug/mLICC: 5-20 ug/mL
Gene symbol	CASP1
Gene Fullname	caspase 1, apoptosis-related cysteine peptidase
Product format	Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive.
Nucleotide accession_num	NM_214162
Protein accession_num	NP_999327.1
Protein name	Caspase-1
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Recombinant CASP1 (Asn120~Asp297) expressed in E.coli
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against CASP1. It has been selected for its ability to recognize CASP1 in immunohistochemical staining and western blotting.
Concentration	0.5 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OACD02184-datasheet.pdf

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Amount: 100 ul

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Delivery expected until 10/30/2025

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