Comparison

DKK4 Antibody

Item no. OACD03063
Manufacturer AVIVA Systems Biology
Amount 100 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IP, IHC, ICC
Specific against Human (Homo sapiens), Pig (Porcine, Sus scrofa domesticus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias dickkopf-4;dickkopf-related protein 4;DKK-4;hDkk-4.
Shipping Condition Cool pack
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
25 kDa
Application Data
Western blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-1:5, 000
Optimal working dilutions must be determined by end user.
Gene symbol
DKK4
Gene Fullname
dickkopf WNT signaling pathway inhibitor 4
Product format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution and storage
2°C to 8°C|-20°C
Description of target
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Nucleotide accession_num
NM_014420
Protein accession_num
NP_055235.1
Protein name
Dickkopf-related protein 4
Clonality
Polyclonal
Purification
Affinity Purified; Protein A Purified
Immunogen
Range: Gln107 - His212
Manufacturer - Specificity
The antibody is a rabbit polyclonal antibody raised against DKK4. It has been selected for its ability to recognize DKK4 in immunohistochemical staining and western blotting.
Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Concentration
0.5 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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