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TOLLIP Antibody

TOLLIP Antibody

Item no.	OACD07940
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Obesity Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunocytochemistry Primary Antibodies Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IP, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	adapter protein;IL-1RAcPIP;toll-interacting protein.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	23 kDa
Application Data	Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5, 000 Optimal working dilutions must be determined by end user.
Gene symbol	TOLLIP
Gene Fullname	toll interacting protein
Product format	Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).
Nucleotide accession_num	NM_001318512
Protein accession_num	NP_001305441.1
Protein name	Toll-interacting protein
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Range: Gln28 - Asp261
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against TOLLIP. It has been selected for its ability to recognize TOLLIP in immunohistochemical staining and western blotting.
Formulation	PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Concentration	0.5 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/30/2025

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