SOX2 Antibody (OAEC04441)

Wet Ice

Ascitic fluid containing 0.03% sodium azide

SOX2 SRY (sex determining region Y)-box 2. Entrez Protein NP_003097. It is a member of the SRY-related HMG-box (SOX) fam ily of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system , and also regulates gene expression in the stom ach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Purified recombinant fragment of SOX2 (aa1-170) expressed in EColi.