« Back
Home /
LILRB1 Antibody

LILRB1 Antibody

Item no.	OAEE00325
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg (C100)
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Adenocarcinoma Myelofibrosis Mesothelioma Flow Cytometry Immunoprecipitation Western Blot Primary Antibodies Astrocytoma Functional Assays
Type	Antibody Monoclonal
Applications	WB, FC, IP, FA
Clone	GHI/75
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b
Purity	> 95% (by SDS-PAGE)
Citations	Riteau B, Menier C, Khalil-Daher I, Martinozzi S, Pla M, Dausset J, Carosella ED, Rouas-Freiss N: HLA-G1 co-expression boosts the HLA class I-mediated NK lysis inhibition. Int Immunol. 2001 Feb;13(2):193-201. Lo Monaco E, Tremante E, Cerboni C, Melucci E, Sibilio L, Zingoni A, Nicotra MR, Natali PG, Giacomini P: Human leukocyte antigen E contributes to protect tumor cells from lysis by natural killer cells. Neoplasia. 2011 Sep;13(9):822-30. Leukocyte Typing V., Schlossman S. et al. (Eds.), Oxford University Press (1995). Banham AH, Colonna M, Cella M, Micklem KJ, Pulford K, Willis AC, Mason DY: Identification of the CD85 antigen as ILT2, an inhibitory MHC class I receptor of the immunoglobulin superfamily. J Leukoc Biol. 1999 Jun;65(6):841-5.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD85 antigen-like family member J;CD85J;Ig-like transcript 2;ILT2;ILT-2;immunoglobulin heavy chain variable region;Immunoglobulin-like transcript 2;leucocyte Ig-like receptor B1;leukocyte immunoglobulin-like receptor subfamily B member 1;leukocyte immunoglobulin-like receptor,subfamily B (with TM and ITIM domains),member 1;LIR1;LIR-1;MIR7;MIR-7;monocyte/macrophage immunoglobulin-like receptor 7;myeloid inhibitory receptor 7;PIRB;PIR-B.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	LILRB1
Gene Fullname	leukocyte immunoglobulin like receptor B1
Product format	Phosphate buffered saline (PBS), pH 7.4
Reconstitution and storage	2°C to 8°C
Description of target	Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Nucleotide accession_num	NM_001081637.2; NM_001081638.3; NM_001081639.3; NM_001278398.2; NM_001278399.2; NM_006669.6
Protein accession_num	NP_001075106.2; NP_001075107.2; NP_001075108.2; NP_001265327.2; NP_001265328.2; NP_006660.4
Protein name	Leukocyte immunoglobulin-like receptor subfamily B member 1
Clonality	Monoclonal
Purification	Purified
Immunogen	Hairy cell leukaemia cells
Manufacturer - Specificity	The mouse monoclonal antibody GHI/75 recognizes CD85j / ILT2, an 110-120 kDa membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells, and weakly on monocytes. It is also expressed on T cell and NK cell subsets (variable, individual).
Formulation	Low endotoxin
Concentration	1 mg/ml
Storage Buffer	Azide free phosphate buffered saline (PBS), approx. pH 7.4; 0.2 um filter sterilized. Endotoxin level is less than 0.01 EU/ug of the protein, as determined by the LAL test.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

OAEE00325-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 0.1 mg (C100)

available

Delivery expected until 1/8/2026

Express Delivery: Save 1 days

Compare

Add to wishlist

Get an offer