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gag-pol Antibody

gag-pol Antibody

Item no.	OAEE00411
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg (C100)
Category	Oncology Antibodies By Cell Type Hematology Lymphoma Western Blot ELISA Primary Antibodies Immunostaining Functional Assays
Type	Antibody Monoclonal
Applications	WB, ELISA, FA
Clone	1696
Specific against	Human Immunodeficiency Virus (HIV)
Host	Mouse
Isotype	IgG1
Purity	> 95% (by SDS-PAGE)
Citations	Lescar J, Brynda J, Rezacova P, Stouracova R, Riottot MM, Chitarra V, Fabry M, Horejsi M, Sedlacek J, Bentley G.A.: Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody. Protein Sci. 1999 Dec;8(12):2686-96. BartonovÃ¡ V, KrÃ¡l V, SieglovÃ¡ I, Brynda J, FÃ¡bry M, HorejsÃ M, KozÃsek M, SaskovÃ¡ KG, Konvalinka J, SedlÃ¡cek J, RezÃ¡covÃ¡ P.: Potent inhibition of drug-resistant HIV protease variants by monoclonalantibodies. Antiviral Res. 2008 Jun;78(3):275-7. Epub 2008 Feb 20. O'Loughlin TL, Greene DN, Matsumura I.: Diversification and specialization of HIV protease function during in vitro evolution. Mol Biol Evol. 2006 Apr;23(4):764-72. Velazquez-Campoy A, Todd MJ, Vega S, Freire E.: Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes. Proc Natl Acad Sci U S A. 2001 May 22;98(11):6062-7. Kovalevsky AY, Chumanevich AA, Liu F, Louis JM, Weber I.T.: Caught in the Act: the 1.5 A resolution crystal structures of the HIV-1 protease and the I54V mutant reveal a tetrahedral reaction intermediate. Biochemistry. 2007 Dec 25;46(51):14854-64. Brower ET, Bacha UM, Kawasaki Y, Freire E.: Inhibition of HIV-2 protease by HIV-1 protease inhibitors in clinical use. Chem Biol Drug Des. 2008 Apr;71(4):298-305. Lapins M, Eklund M, Spjuth O, Prusis P, Wikberg J.E.: Proteochemometric modeling of HIV protease susceptibility. BMC Bioinformatics. 2008 Apr 10;9(1):181
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	GAG-POL
Gene Fullname	Gag-Pol polyprotein
Product format	Phosphate buffered saline (PBS), pH 7.4
Reconstitution and storage	2°C to 8°C
Protein name	Gag-Pol polyprotein
Clonality	Monoclonal
Purification	Purified
Immunogen	Bacterially expressed full-length HIV-1 protease
Manufacturer - Specificity	The antibody 1696 recognizes free N-terminus of mature HIV protease (HIV-1 and HIV-2), an enzyme that hydrolyzes polyproteins of HIV viruses into functional proteins. The antibody 1696 does not react with the precursor.
Formulation	Azide free
Concentration	1 mg/ml
Storage Buffer	Azide free phosphate buffered saline (PBS), approx. pH 7.4; 0.2 um filter sterilized.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg (C100)

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Delivery expected until 1/8/2026

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