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Tubb3 Antibody

Tubb3 Antibody

Item no.	OAEE00578
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg (C100)
Category	Neuroscience Neural Lineage Markers Antibodies Cell Biology Cytoskeleton Flow Cytometry Immunohistochemistry Western Blot Immunocytochemistry Primary Antibodies Mikrotubules Neurodegeneration Markers Immunochemistry
Type	Antibody Monoclonal
Applications	FC, ICC
Clone	TU-20
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Dog (Canine, Canis lupus familiaris), Pig (Porcine, Sus scrofa domesticus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	FITC
Citations	Draberova E, Lukas Z, Ivanyi D, Viklicky V, Draber P: Expression of class III beta-tubulin in normal and neoplastic human tissues. Histochem Cell Biol. 1998 Mar;109(3):231-9. JirÃ¡sek T, Cipro S, MusilovÃ¡ A, KubecovÃ¡ M, Mandys V: Expression of class III beta-tubulin in colorectal carcinomas: an immunohistochemical study using TU-20 & TuJ-1 antibody. Indian J Med Res. 2009 Jan;129(1):89-94. Theodorou E, Dalembert G, Heffelfinger C, White E, Weissman S, Corcoran L, Snyder M: A high throughput embryonic stem cell screen identifies Oct-2 as a bifunctional regulator of neuronal differentiation. Genes Dev. 2009 Mar 1;23(5):575-88. Katsetos CD, Draberova E, Smejkalova B, Reddy G, Bertrand L, de ChadarÃ©vian J-P, Legido A, Nissanov J, Baas PW, Draber P: Class III beta-Tubulin and gamma-Tubulin are Co-expressed and form Complexes in Human Glioblastoma Cells. Neurochem Res (2007) 32:1387-1398. Jirasek T, Pisarikova E, Viklicky V, Mandys V: Expression of class III beta-tubulin in malignant epithelial tumours: animmunohistochemical study using TU-20 and TuJ-1 antibodies. Folia Histochem Cytobiol. 2007;45(1):41-5. Kukharskyy V, Sulimenko V, MacÅ¯rek L, Sulimenko T, DrÃ¡berovÃ¡ E, DrÃ¡ber P: Complexes of gamma-tubulin with nonreceptor protein tyrosine kinases Src and Fyn in differentiating P19 embryonal carcinoma cells.Exp Cell Res. 2004 Aug 1;298(1):218-28. Peknicova J, Kubatova A, Sulimenko V, Draberova E, Viklicky V, Hozak P, Draber P: Differential subcellular distribution of tubulin epitopes in boar spermatozoa:recognition of class III beta-tubulin epitope in sperm tail.Biol Reprod. 2001 Sep;65(3):672-9.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	beta-4;CDCBM;CDCBM1;CFEOM3;CFEOM3A;class III beta-tubulin;FEOM3;TUBB4;tubulin beta-3 chain;tubulin beta-4 chain;tubulin beta-III;tubulin,beta 3.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	TUBB3
Gene Fullname	tubulin beta 3 class III
Product format	Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Reconstitution and storage	2°C to 8°C
Description of target	Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance.
Nucleotide accession_num	NM_023279.2
Protein accession_num	NP_075768.1
Protein name	Tubulin beta-3 chain
Clonality	Monoclonal
Purification	Purified by size-exclusion chromatography
Immunogen	Peptide (C) 441-448 coupled to maleimide-activated keyhole limpet hemocyanin via cysteine added to the N-terminus of the neuron-specific peptide.
Manufacturer - Specificity	The antibody TU-20 recognizes C-terminal peptide sequence ESESQGPK (aa 441-448) of neuron-specific human betaIII-tubulin.
Formulation	FITC
Concentration	1 mg/ml
Storage Buffer	Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg (C100)

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Delivery expected until 2/12/2026

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