SOX2 Antibody (OAGA01620)

Wet Ice

Liquid. 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Purified by antigen-affinity chromatography.