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SP1 Antibody

SP1 Antibody

Item no.	OAGA03622
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Neural Transcription Factors Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Melanoma Sarcoma Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies CHiP Neuronal Cell Markers Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IP, ICC, IHC-P, CHIP
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Sp1 transcription factor
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	81 kDa
Manufacturer - Application Additional Information	WB: 1:500-1:3000ICC: 1:100-1:1000IF: 1:100-1:1000IHC-P: 1:100-1:1000IP: 1:100-1:500Optimal dilutions should be determined by the end user.
Gene symbol	SP1
Gene Fullname	Sp1 transcription factor
Product format	Liquid. 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Reconstitution and storage	Keep as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Description of target	Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
Nucleotide accession_num	NM_001251825.1
Protein accession_num	NP_001238754.1
Protein name	transcription factor Sp1
Clonality	Polyclonal
Purification	Purified by antigen-affinity chromatography
Immunogen	Recombinant protein encompassing a sequence within the center region of human SP1. The exact sequence is proprietary.
Homology	Bovine, Rhesus Monkey(>80% identity)
Concentration	0.06 mg/ml
Storage Buffer	1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/30/2025

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