GDF6 Antibody

Polyclonal Antibody

Wet Ice

GDF6

Liquid

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis.

NP_001001557.1

Polyclonal

Recombinant protein encompassing a sequence within the center region of human GDF6. The exact sequence is proprietary.

1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.