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TET1 Antibody

TET1 Antibody

Item no.	OAGA08281
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Antibodies Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies CHiP Immunochemistry
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, IP, IHC, ICC, CHIP
Clone	GT1462
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG2a
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	LCX,CXXC6,bA119F7.1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Applications	ICC, IF, IHC-FFPE, IP, WB, CHIP
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	235 kDa
Manufacturer - Application Additional Information	CHIP: Assay-dependent dilution ICC/IF: 1:100~1000 IHC-FFPE: 1:100~1000 IP: 1:100~500 WB: 1:500~3000. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
Gene symbol	TET1
Gene Fullname	tet methylcytosine dioxygenase 1
Product format	Liquid PBS
Reconstitution and storage	Store as a concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze/thaw cycles.
Description of target	Dioxygenase that specifically binds methylcytosine (5mC), a minor base in mammalian DNA found in repetitive DNA elements that is crucial for retrotransposon silencing and mammalian development. Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. 5-hydroxymethylcytosine (hmC) is present in ES cells and is enriched in the brain, especially in Purkinje neurons. May play a role in the fetal development of heart, lung and brain.
Nucleotide accession_num	NM_030625.2
Protein accession_num	NP_085128.2
Protein name	methylcytosine dioxygenase TET1
Clonality	Monoclonal
Purification	Affinity purified by Protein G.
Immunogen	Recombinant protein encompassing a sequence within the center region of human TET1. The exact sequence is proprietary.
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/30/2025

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