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RBBP8 Antibody

RBBP8 Antibody

Item no.	OAGA08794
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies CHiP By Organ Breast Cancer Immunochemistry
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, IP, ICC, CHIP
Clone	1900000000
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	RIM,COM1,CTIP,JWDS,SAE2,SCKL2
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IP, WB: 1:500-1:1000 (3% Milk/TBST overnight), ChIP assay, PLA. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Gene symbol	RBBP8
Gene Fullname	RB binding protein 8, endonuclease
Product format	Liquid
Reconstitution and storage	Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.
Description of target	The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Nucleotide accession_num	NM_002894.2
Protein accession_num	NP_002885.1
Protein name	DNA endonuclease RBBP8
Clonality	Monoclonal
Purification	Protein G purified
Immunogen	Human CtIP
Concentration	1.3 mg/ml
Storage Buffer	Phosphate-buffered saline, pH 7.4, containing no preservatives

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/30/2025

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