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TRIM33 Antibody - N-terminal

TRIM33 Antibody - N-terminal

Item no.	OAPB01767
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg
Category	Oncology Neuroscience Neural Lineage Markers Targets for Rodent Neurosciences Antibodies By Cell Type Carcinoma Adenocarcinoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Colorectal Cancer Immunostaining Neurodegeneration Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E3 ubiquitin-protein ligase TRIM33;ECTO;ectodermin homolog;protein Rfg7;PTC7;RET-fused gene 7 protein;RFG7;RING-type E3 ubiquitin transferase TRIM33;TF1G;TIF1G;TIF1-gamma;TIF1GAMMA;TIFGAMMA;Transcription intermediary factor 1-gamma;transcriptional intermediary factor 1 gamma;Tripartite motif-containing protein 33.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	Predicted: 70, 124 kDa Observed: 70 kDa
Gene symbol	TRIM33
Gene Fullname	tripartite motif containing 33
Product format	Liquid. TRIM33 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
Nucleotide accession_num	NM_015906.3
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/NP_056990
Protein name	E3 ubiquitin-protein ligase TRIM33\|E3 ubiquitin-protein ligase TRIM33 isoform alpha [Homo sapiens]
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	TRIM33 antibody was raised against an 18 amino acid peptide near the center of human TRIM33. The immunogen is located within amino acids 580 - 630 of TRIM33.
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 2/12/2026

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