ADRB2 Antibody

Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies

47 kDa

ADRB2

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

AR-Beta2 Polyclonal Antibody detects endogenous levels of AR-Beta2 protein.