IL12A Antibody - middle region

Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies

25 kDa

IL12A

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

IL-12A Polyclonal Antibody detects endogenous levels of IL-12A protein.