NGFR Antibody - middle region

Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies

75 kDa

NGFR

Liquid PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

NGFR p75 Polyclonal Antibody detects endogenous levels of NGFR p75 protein.