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SMARCA4 Antibody, KO Validated

SMARCA4 Antibody, KO Validated

Item no.	PRS-13-315-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Melanoma Sarcoma Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IF, IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	SMARCA4
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	SMARCA4 Antibody: BRG1,SNF2,SWI2,MRD16,RTPS2,BAF190,SNF2L4,SNF2LB,hSNF2b,BAF190A,BRG1,SNF2B,Transcription activator BRG1,ATP-dependent helicase SMARCA4
Shipping Condition	Cool pack
Available
Specificity	Human
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 180kDa
Manufacturer - Research Area	Cancer, Neuroscience, Stem Cell
Background	The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
By Type	Cancer, Neuroscience, Stem Cell
Badges	KO
Modifications	None
Purification	Affinity purification
Validation	Antibody is Knockout validated.
Positive Control 1	OVCAR3
Positive Control 2	HeLa
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:50 - 1:100 IF: 1:20 - 1:50
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 30-130 of human SMARCA4 (NP_003063.2).
Clonality	Polyclonal
NCBI Official Name	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.
Validation	Antibody is Knockout validated.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 12/4/2025

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