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SCN8A Antibody

SCN8A Antibody

Item no.	PRS-13-368-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Antibodies Western Blot Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	SCN8A
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Specificity	Human
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 165kDa
Manufacturer - Research Area	Neuroscience
Background	This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.
By Type	Neuroscience
Modifications	None
Purification	Affinity purification
Positive Control 1	K-562
Positive Control 2	SH-SY5Y
Positive Control 3	293T
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:200 - 1:1000
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1350-1440 of human SCN8A (NP_055006.1).
Clonality	Polyclonal
NCBI Official Name	sodium voltage-gated channel alpha subunit 8
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.
Manufacturer - Additional Names	BFIS5, CERIII, CIAT, EIEE13, MED, MYOCL2, NaCh6, Nav1.6, PN4, sodium channel protein type 8 subunit alpha, hNa6/Scn8a voltage-gated sodium channel, sodium channel, voltage gated, type VIII, alpha subunit, voltage-gated sodium channel subunit alpha Nav1.6, voltage-gated sodium channel type VIII alpha protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 11/6/2025

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