SCN1B Antibody

Blue Ice

Observed: 30kDa

Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.

None

SH-SY5Y

HeLa

Mouse brain

batch dependent

WB: 1:500 - 1:2000
IHC: 1:100 - 1:200

Polyclonal

Homo sapiens