PLA2G10 Antibody

Blue Ice

Observed: 18kDa

This gene encodes a member of the phospholipase A2 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This calcium-dependent enzyme hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. In one example, this enzyme catalyzes the release of arachidonic acid from cell membrane phospholipids, thus playing a role in the production of various inflammatory lipid mediators, such as prostaglandins. The encoded protein may promote the survival of breast cancer cells through its role in lipid metabolism.

None

K-562

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PLA2G10 (NP_003552.1).

phospholipase A2 group X

Optimal dilutions for each application to be determined by the researcher.