Comparison

CRKL Antibody, KO Validated

Item no. PRS-14-122-100uL
Manufacturer ProSci
Amount 100 uL
Quantity options 100 uL
Category
Type Antibody Primary
Format Liquid
Applications WB, IF
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
NCBI CRKL
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CRKL,v-crk sarcoma virus CT10 oncogene homolog (avian)-like,v-crk avian sarcoma virus CT10 oncogene homolog-like,
Shipping Condition Cool pack
Available
Specificity Human,Mouse,Rat
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight
Observed: 37kDa
Manufacturer - Research Area
Cancer, Immunology, Neuroscience, Signal Transduction
Background
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
By Type
Cancer, Immunology, Neuroscience, Signal Transduction
Badges
KO
Modifications
None
Purification
Affinity purification
Validation
Antibody is Knockout validated.
Positive Control 1
LO2
Positive Control 2
Jurkat
Positive Control 3
SKOV3
Positive Control 4
Mouse brain
Positive Control 5
Rat heart
Concentration
batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note
WB: 1:500 - 1:2000
IF: 1:50 - 1:200
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human CRKL (NP_005198.1).
Clonality
Polyclonal
NCBI Official Name
v-crk avian sarcoma virus CT10 oncogene homolog-like
NCBI Organism
Homo sapiens
User Note
Optimal dilutions for each application to be determined by the researcher.
Validation
Antibody is Knockout validated.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 uL
Available: In stock
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