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DOT1L Antibody

DOT1L Antibody

Item no.	PRS-14-366-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	DOT1L
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 170kDa
Manufacturer - Research Area	Other
Background	The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes.
By Type	Other
Modifications	None
Purification	Affinity purification
Positive Control 1	Mouse liver
Positive Control 2	Rat liver
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:50 - 1:200
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1400-1500 of human DOT1L (NP_115871.1).
Clonality	Polyclonal
NCBI Official Name	DOT1 like histone lysine methyltransferase
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.
Manufacturer - Additional Names	DOT1, KMT4, histone-lysine N-methyltransferase, H3 lysine-79 specific, DOT1 like histone H3K79 methyltransferase, DOT1-like histone methyltransferase, DOT1-like protein, DOT1-like, histone H3 methyltransferase, H3-K79-HMTase, histone H3-K79 methyltransferase, histone methyltransferase DOT1L, lysine N-methyltransferase 4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 12/4/2025

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