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EIF4EBP1 Antibody, KO Validated

EIF4EBP1 Antibody, KO Validated

Item no.	PRS-14-450-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies Immunohistochemistry Western Blot Immunofluorescence Endocrine Regulation of Lipid Metabolism Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	EIF4EBP1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	4E-BP1 Antibody: BP-1,4EBP1,4E-BP1,PHAS-I,Eukaryotic translation initiation factor 4E-binding protein 1,Phosphorylated heat- and acid-stable protein regulated by insulin 1
Shipping Condition	Cool pack
Available
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 17kDa
Manufacturer - Research Area	Obesity, Signal Transduction
Background	This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
By Type	Obesity, Signal Transduction
Badges	KO
Modifications	None
Purification	Affinity purification
Validation	Antibody is Knockout validated.
Positive Control 1	MCF7
Positive Control 2	HeLa
Positive Control 3	SH-SY5Y
Positive Control 4	NIH/3T3
Positive Control 5	Mouse fat
Positive Control 6	Mouse heart
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:1000 IHC: 1:50 - 1:200 IF: 1:100 - 1:200
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human EIF4EBP1 (NP_004086.1).
Clonality	Polyclonal
NCBI Official Name	eukaryotic translation initiation factor 4E binding protein 1
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.
Validation	Antibody is Knockout validated.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 1/1/2026

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