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SET Antibody

SET Antibody

Item no.	PRS-14-474-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Oncology Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Hematology Leukemia Western Blot Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody Primary
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	SET
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	SET,SET translocation (myeloid leukemia-associated),2PP2A,I2PP2A,PHAPII,TAF-IBETA,SET,translocation,IGAAD,inhibitor-2 of protein phosphatase-2A,Inhibitor of GZMA-activated DNAse,TAF-I,IPP2A2
Shipping Condition	Cool pack
Available
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 33kDa
Manufacturer - Research Area	Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Background	The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.
By Type	Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Modifications	None
Purification	Affinity purification
Positive Control 1	HeLa
Positive Control 2	293T
Positive Control 3	BT-474
Positive Control 4	Mouse spleen
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 146-277 of human SET (NP_003002.2).
Clonality	Polyclonal
NCBI Official Name	SET nuclear oncogene
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 12/4/2025

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