IDH3G Antibody

Blue Ice

Observed: 43kDa

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.

None

U-87MG

HepG2

NIH/3T3

batch dependent

WB: 1:500 - 1:2000

Polyclonal

Homo sapiens

isocitric dehydrogenase subunit gamma, isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, gamma subunit, isocitrate dehydrogenase [NAD] subunit gamma, OTTHUMP00000025988, OTTHUMP00000025987, OTTHUMP00000025984, NAD+-specific ICDH, NAD(+)-specific ICDH subunit gamma, NAD (H)-specific isocitrate dehydrogenase gamma subunit, IDH-gamma, H-IDHG, isocitrate dehydrogenase 3 (NAD+) gamma, IDH3G