Comparison

MAN1B1 Antibody

Item no. PRS-15-201-100uL
Manufacturer ProSci
Amount 100 uL
Quantity options 100 uL
Category
Type Antibody Primary
Format Liquid
Applications WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
NCBI MAN1B1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Shipping Condition Cool pack
Available
Specificity Human,Mouse,Rat
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight
Observed: 80kDa
Manufacturer - Research Area
Other
Background
This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1, 2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.
By Type
Other
Modifications
None
Purification
Affinity purification
Positive Control 1
U-87MG
Positive Control 2
A-549
Positive Control 3
HeLa
Positive Control 4
A-431
Positive Control 5
Mouse kidney
Positive Control 6
Mouse spleen
Concentration
batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note
WB: 1:500 - 1:2000
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human MAN1B1 (NP_057303.2).
Clonality
Polyclonal
NCBI Official Name
mannosidase alpha class 1B member 1
NCBI Organism
Homo sapiens
User Note
Optimal dilutions for each application to be determined by the researcher.
Manufacturer - Additional Names
ERMAN1, ERManI, MANA-ER, MRT15, endoplasmic reticulum mannosyl-oligosaccharide 1, 2-alpha-mannosidase, ER alpha 1, 2-mannosidase, Man9GlcNAc2-specific processing alpha-mannosidase, endoplasmic Reticulum Class I alpha-mannosidase, endoplasmic reticulum mannosyl-oligosaccharide 1, 2-alpha-mannosidase 1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 uL
Available: In stock
available

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