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TGFBR2 Antibody

TGFBR2 Antibody

Item no.	PRS-15-398-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Oncology Neuroscience Neuroinflammation Antibodies By Cell Type Carcinoma Glioma Cell Biology Cell Culture Cytokines Mesothelioma Immunohistochemistry Western Blot Primary Antibodies By Organ Colorectal Cancer
Type	Antibody Primary
Format	Liquid
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	TGFBR2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	TGFBR2,HNPCC6,MFS2,RIIC,Tbeta,AAT3,FAA3,LDS1B,LDS2B,TAAD2,TGFR-2,TGFbeta-RII
Shipping Condition	Cool pack
Available
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 75kDa
Manufacturer - Research Area	Cell Cycle, Signal Transduction, Stem Cell
Background	This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
By Type	Cell Cycle, Signal Transduction, Stem Cell
Modifications	None
Purification	Affinity purification
Positive Control 1	HT-29
Positive Control 2	A-549
Positive Control 3	Mouse lung
Positive Control 4	Mouse spleen
Positive Control 5	Mouse brain
Positive Control 6	Mouse kidney
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 23-280 of human TGFBR2 (NP_003233.4).
Clonality	Polyclonal
NCBI Official Name	transforming growth factor, beta receptor II (70/80kDa)
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 11/6/2025

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