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CYP11B2 Antibody

CYP11B2 Antibody

Item no.	PRS-15-536-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Western Blot Immunofluorescence Enzymes Prostaglandin Synthases Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	CYP11B2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cytochrome P450 11B2,mitochondrial,Aldosterone synthase,ALDOS,Aldosterone-synthesizing enzyme,CYPXIB2,Cytochrome P-450Aldo,Cytochrome P-450C18,Steroid 18-hydroxylase,CYP11B2
Shipping Condition	Cool pack
Available
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 50kDa
Manufacturer - Research Area	Other
Background	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.
By Type	Other
Modifications	None
Purification	Affinity purification
Positive Control 1	HepG2
Positive Control 2	MCF7
Positive Control 3	293T
Positive Control 4	Mouse brain
Positive Control 5	Mouse liver
Positive Control 6	Rat liver
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:1000 IHC: 1:50 - 1:100 IF: 1:50 - 1:100
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human CYP11B2 (NP_000489.3).
Clonality	Polyclonal
NCBI Official Name	Cytochrome P450 11B2, mitochondrial
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 1/1/2026

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