Comparison

DHFR Antibody

Item no. PRS-16-410-100uL
Manufacturer ProSci
Amount 100 uL
Quantity options 100 uL
Category
Type Antibody Primary
Format Liquid
Applications WB, IF
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
NCBI DHFR
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias DHFRP1,DYR,dihydrofolate reductase
Shipping Condition Cool pack
Available
Specificity Human,Mouse
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight
Observed: 19kDa
Manufacturer - Research Area
Cancer, Cell Cycle, Signal Transduction
Background
Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene.
By Type
Cancer, Cell Cycle, Signal Transduction
Modifications
None
Purification
Affinity purification
Positive Control 1
HeLa
Positive Control 2
22Rv1
Positive Control 3
K-562
Positive Control 4
HL-60
Positive Control 5
THP-1
Positive Control 6
Raji
Concentration
batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note
WB: 1:500 - 1:2000
IF: 1:50 - 1:200
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-187 of human DHFR (NP_000782.1).
Clonality
Polyclonal
NCBI Official Name
dihydrofolate reductase
NCBI Organism
Homo sapiens
User Note
Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 uL
Available: In stock
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