TXNRD1 Antibody

Blue Ice

Observed: 65kDa

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

None

HepG2

Mouse heart

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Recombinant protein of human TXNRD1

thioredoxin reductase 1

Optimal dilutions for each application to be determined by the researcher.