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MMP8 Antibody

MMP8 Antibody

Item no.	PRS-18-416-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Antibodies Cell Biology Western Blot Immunofluorescence Cell Stainings ECM Cardiovascular Research Atherosclerosis Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	MMP8
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Neutrophil collagenase,Matrix metalloproteinase-8,MMP-8,PMNL collagenase,PMNL-CL,MMP8,CLG1
Shipping Condition	Cool pack
Available
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 65kDa
Manufacturer - Research Area	Cancer, Cell Cycle, Immunology, Signal Transduction
Background	This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
By Type	Cancer, Cell Cycle, Immunology, Signal Transduction
Modifications	None
Purification	Affinity purification
Positive Control 1	A-549
Positive Control 2	HL-60
Positive Control 3	HepG2
Positive Control 4	Jurkat
Positive Control 5	MCF7
Positive Control 6	Mouse liver
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IF: 1:50 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 101-467 of human MMP8 (NP_002415.1).
Clonality	Polyclonal
NCBI Official Name	Neutrophil collagenase
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 12/4/2025

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