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PDE1B Antibody

PDE1B Antibody

Item no.	PRS-18-502-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot Immunofluorescence Cardiovascular Research Thrombosis & Hemostasis Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	PDE1B
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B,Cam-PDE 1B,63 kDa Cam-PDE,PDE1B,PDE1B1,PDES1B
Shipping Condition	Cool pack
Available
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 59kDa
Manufacturer - Research Area	Apoptosis, Cell Cycle
Background	The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
By Type	Apoptosis, Cell Cycle
Modifications	None
Purification	Affinity purification
Positive Control 1	NCI-H460
Positive Control 2	THP-1
Positive Control 3	Mouse brain
Positive Control 4	Mouse spleen
Positive Control 5	Mouse spinal cord
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:50 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 190-536 of human PDE1B (NP_000915.1).
Clonality	Polyclonal
NCBI Official Name	Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1B
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 12/4/2025

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