NFkB p100 / p52 Antibody

Blue Ice

Observed: 33kDa

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.

None

HT-29

HeLa

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

A synthetic peptide of human NFkB p100 / p52

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

Optimal dilutions for each application to be determined by the researcher.